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Abstract
Case Report
A case of allergic bronchopulmonary mycosis resulting from Schizophyllum commune: Possibility of sinobronchial allergic mycosis (SAM) syndrome
Kenta Yamamuraa Noriyuki Ohkuraa Haruhiko Ogawab Shingo Nishikawac Johsuke Haraa Kazuo Kasaharaa Masaki Fujimurad
aRespiratory Medicine, Kanazawa University Hospital
bRespiratory Medicine, Ishikawa-ken Saiseikai Kanazawa Hospital
cRespiratory Medicine, Kanazawa Social Insurance Hospital
dRespiratory Medicine, National Hospital Organization Nanao Hospital
ABSTRACT
A 68-year-old woman was admitted to our hospital because of chronic cough. A paranasal sinuses radiograph showed fluid retention in the right maxillary sinus, and chest computed tomography showed hyperattenuated mucoid impaction and consolidation in the lingular segment. Bronchoscopy showed a mucous plug in the lingular bronchus. A biopsy specimen of a mucous plug obtained by bronchoscopy showed fungal hyphae and numerous eosinophils, with evidence of lung tissue eosinophilia. We detected both precipitating and specific IgE antibodies against Schizophyllum commune and performed a bronchoprovocation test using crude extract of S. commune, which led to the definitive diagnosis of allergic bronchopulmonary mycosis caused by S. commune. Because sinusitis also improved when the Sc-ABPM treatment was applied, a possibility of SAM syndrome was suggested.
KEYWORDS
Allergic bronchopulmonary mycosis Schizophyllum commune Cough variant asthma Sinobronchial allergic mycosis (SAM) syndrome
Received 22 Feb 2013 ／ Accepted 7 Aug 2013
AJRS, 3(3): 380-384, 2014
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