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Article in Japanese
Abstract
Topics Series Allergy, immunology and inflammation
Risk factor
Takahiko Horiguchi Mamoru Shiga
Department of Respiratory Medicine II, Fujita Health University School of Medicine
ABSTRACT
Major risk factors for bronchial asthma include aspirin-intolerant asthma (AIA), exercise-induced asthma (EIA), and asthma in the elderly. AIA is characterized by complications of eosinophilic rhinosinusitis with nasal polyps and the onset of cyclooxygenase-1 (COX-1) inhibitor-induced severe upper and lower respiratory tract symptoms, which suggests that specific measures against the misuse of COX-1 inhibitors are needed. The pathology of EIA in athletes has been gradually elucidated. Administration of β-agonists prior to exercise is useful, but additional long-term control medication is recommended if the condition is uncontrolled. If such drug administration is performed, caution should be exercised to ensure that the drug is not a prohibited doping agent. Asthma in the elderly is quite likely to be underdiagnosed, underestimated, or undertreated. Therefore treatment focusing on individual risk factors is important.
KEYWORDS
Bronchial asthma Aspirin-intolerant asthma (AIA) Exercise-induced asthma (EIA) Asthma in the elderly Risk factor
AJRS, 3(2): 186-193, 2014
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