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Article in Japanese
Abstract
Case Report
A case of Waldenström macroglobulinemia with lung tumors, interstitial infiltrations, and hypercalcemia
Hiromi Yamane Kosuke Kashiwabara Hideyuki Tanaka
Department of Respiratory Medicine, National Hospital Organization Kumamoto Medical Center
ABSTRACT
An 83-year-old man was admitted to our hospital because of visual loss, photophobia, and dyspnea on exertion. Monoclonal gammopathy (IgM-λ type) was detected in the serum and lymphoplasmacytic cells proliferated in the bone marrow. Chest CT scan showed tumor shadows in the right middle and lower lobes and interstitial shadows in both lung fields. These shadows were diagnosed as pulmonary involvements of Waldenström macroglobulinemia because transbronchial lung biopsy specimen showed IgM-λ-positive lymphoplasmacytic cells infiltrated in both tumor and lung interstitium. This patient developed blood hyperviscosity and hypercalcemia refractory to therapy.
KEYWORDS
Macroglobulinemia TBLB Hyperviscosity syndrome Hypercalcemia
Received 6 Jun 2013 ／ Accepted 26 Aug 2013
AJRS, 3(1): 111-115, 2014
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