Treatment of pulmonary metastasis of dermatofibrosarcoma protuberans with imatinib mesylate: A case report
Makoto Furugena Masashi Nakamatsua Eriko Atsumia,b Kazuya Miyagia Shusaku Haranagaa Jiro Fujitaa
aDepartment of Infection, Respiratory and Digestive Medicine (First Department of Internal Medicine), Graduate School of Medicine, University of the Ryukyus
bDepartment of Pathology, University of the Ryukyus Hospital
A 60-year-old man with a previous history of complete resection of dermatofibrosarcoma protuberans (DFSP) from his left forearm at 49 years of age underwent partial resection of the left upper pulmonary lobe for multiple pulmonary tumors. He was diagnosed with pulmonary metastasis of DFSP. Imatinib mesylate is reportedly effective for DFSP by inhibition of the platelet-derived growth factor receptor. In this case, we treated the pulmonary metastasis of DFSP with imatinib mesylate, and the pulmonary lesion subsequently decreased in size. We herein describe a rare case of pulmonary metastasis of DFSP treated with imatinib mesylate in a Japanese patient.
Dermatofibrosarcoma protuberans (DFSP) Pulmonary metastasis Imatinib mesylate
Received 4 Jun 2013 / Accepted 24 Sep 2013
AJRS, 3(1): 107-110, 2014