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Abstract
Case Report
A case of the malignant pleural mesothelioma diagnosed by endoscopic ultrasound-guided fine-needle aspiration
Koichi Saruwataria,b,＊ Fumiya Imamurab Kaori Tsumorib Takahiro Uratac Seiji Fukudad Hirotsugu Kohrogia
aDepartment of Respiratory Medicine, Kumamoto University Hospital
bDepartment of Respiratory Medicine, Kumamoto Red Cross Hospital
cDepartment of Gastroenterology, Kumamoto Red Cross Hospital
dDepartment of Pathology, Kumamoto Red Cross Hospital
ABSTRACT
A 79-year-old man presented for back pain and dyspnea. An enhanced CT scan showed mediastinal mass attaching the esophagus and descending aorta with bilateral pleural effusion. The pleural effusion showed an elevation of hyaluronic acid and an atypical class V cell. We performed an endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) for a mediastinal mass. A histopathological examination showed large atypical epithelial cells and immunohistochemically positive for carletinin and D2-40, but negative for thyroid tissue factor-1 (TTF-1) and CEA. Therefore we diagnosed it as epithelioid malignant mesothelioma. The patient underwent pleurodesis and was then administered with carboplatin+pemetrexed, and the tumor size was reduced. EUS-FNA was a useful procedure for definitive diagnosis for malignant pleural mesothelioma situated along the esophagus and aorta.
KEYWORDS
Malignant pleural mesothelioma Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA)
Received 29 Mar 2013 ／ Accepted 2 Sep 2013
AJRS, 3(1): 65-69, 2014
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