A case of giant anterior mediastinal mass by T-cell lymphoblastic lymphoma that progressed rapidly
Kazuhisa Nakashimaa,b Junya Inatab Masashi Kaneharab Miho Konoc Yasuo Iwamotoc Masaaki Nodad Shinichi Takadae Hideki Asaokuf
aDepartment of Respiratory Medicine, Shizuoka Cancer Center
bDepartment of Respiratory Medicine, Hiroshima City Hospital
cDepartment of Medical Oncology, Hiroshima City Hospital
dDepartment of Internal Medicine, Hiroshima City Hospital
eDepartment of Pathology, Hiroshima City Hospital
fDepartment of Hematology, Hiroshima Red Cross Hospital & Atomic-Bomb Survivors Hospital
The patient was an 18-year-old man. He complained of cough from a month ago. He became dyspneic, fell into cardiopulmonary arrest, and was resuscitated on site. Chest CT scanning showed a large anterior mediastinal mass with severe tracheal stenosis. The final diagnosis by percutaneous needle biopsy was T-cell lymphoblastic lymphoma (T-LBL). So we started CHOP therapy (cyclophosphamide, hydroxydaunorubicin, vincristine, and prednisolone). The tumor showed a reduction in mass size and improvement of respiration after the first course of chemotherapy. After extubation, the patient transferred to another hospital for chemotherapy. In a case of this kind, which shows a large anterior mediastinal mass in a young patient, we must consider the possibility of T-LBL.
T-cell lymphoblastic lymphoma Giant anterior mediastinal mass Airway stenosis
Received 6 Mar 2013 / Accepted 13 Jul 2013
AJRS, 3(1): 61-64, 2014