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Abstract

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Article in Japanese

Case Report

A case of giant anterior mediastinal mass by T-cell lymphoblastic lymphoma that progressed rapidly

Kazuhisa Nakashimaa,b  Junya Inatab  Masashi Kaneharab  Miho Konoc  Yasuo Iwamotoc  Masaaki Nodad  Shinichi Takadae  Hideki Asaokuf 

aDepartment of Respiratory Medicine, Shizuoka Cancer Center
bDepartment of Respiratory Medicine, Hiroshima City Hospital
cDepartment of Medical Oncology, Hiroshima City Hospital
dDepartment of Internal Medicine, Hiroshima City Hospital
eDepartment of Pathology, Hiroshima City Hospital
fDepartment of Hematology, Hiroshima Red Cross Hospital & Atomic-Bomb Survivors Hospital

ABSTRACT

The patient was an 18-year-old man. He complained of cough from a month ago. He became dyspneic, fell into cardiopulmonary arrest, and was resuscitated on site. Chest CT scanning showed a large anterior mediastinal mass with severe tracheal stenosis. The final diagnosis by percutaneous needle biopsy was T-cell lymphoblastic lymphoma (T-LBL). So we started CHOP therapy (cyclophosphamide, hydroxydaunorubicin, vincristine, and prednisolone). The tumor showed a reduction in mass size and improvement of respiration after the first course of chemotherapy. After extubation, the patient transferred to another hospital for chemotherapy. In a case of this kind, which shows a large anterior mediastinal mass in a young patient, we must consider the possibility of T-LBL.

KEYWORDS

T-cell lymphoblastic lymphoma  Giant anterior mediastinal mass  Airway stenosis 

Received 6 Mar 2013 / Accepted 13 Jul 2013

AJRS, 3(1): 61-64, 2014

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