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Article in Japanese
Abstract
Topics Series Advances in lung cancer therapy
Update on pathological diagnosis: The new adenocarcinoma classification and morphological characteristics of adenocarcinomas with recently identified gene alterations
Department of Pathology and Molecular Diagnostics, Aichi Cancer Center
ABSTRACT
In addition to classical histological diagnosis, patient selection for personalized medicine is appended to a current role of pathological diagnosis. In 2001, a new adenocarcinoma classification was proposed, presenting new concepts of lung cancers. Since then, the new classification has been applied in clinical practice, and the results have been reported. In this article, we briefly review this classification and discuss the practical problem in applying it to clinical practice. Moreover, we review the pathological-molecular correlation of the novel gene alterations that were identified after publication of the new classification.
KEYWORDS
Lung adenocarcinoma IASLC/ATS/ERS adenocarcinoma classification ROS1 RET NRG1
AJRS, 3(1): 16-22, 2014
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