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Abstract
Case Report
A case of primary ciliary dyskinesia developed by a woman in her 60s
Keitaro Nakamotoa,b Noboru Takayanagia Eriko Kawatea Chie Otaa Tsutomu Yanagisawaa Yutaka Sugitaa
aDepartment of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center
bDepartment of Respiratory Medicine, Kyorin University School of Medicine
ABSTRACT
A 62-year-old woman was referred to our hospital because of cough, sputum, and an abnormal chest X-ray. Chest CT showed thickening of the bronchial walls and bronchiectasis and centrilobular small nodular shadows. Her symptoms disappeared at her first hospital visit, but during follow-up, she sometimes suffered from lower respiratory tract infections. Electron microscopic examination of biopsies of her bronchial mucosa showed a defect of the inner and outer dynein arms of the cilia. We diagnosed her as having primary ciliary dyskinesia. Her symptoms improved after treatment with a low-dose macrolide. When patients with repeated pulmonary tract infections are examined, primary ciliary dyskinesia should be considered in the differential diagnoses.
KEYWORDS
Primary ciliary dyskinesia Respiratory tract infection Cilia
Received 4 Jun 2013 ／ Accepted 8 Aug 2013
AJRS, 2(6): 841-845, 2013
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