Higher cerebral dysfunction in a patient with cerebral venous sinus thrombosis complicated by lung cancer: A case report
Eri Tomioka Shotaro Chubachi Joji Horio Minako Sato Tatsu Matsuzaki Takeshi Terashima
Department of Respiratory Internal Medicine, Tokyo Dental College Ichikawa General Hospital
Cerebral venous sinus thrombosis (CVST) is a relatively infrequent disease in oncology, and accompanied by lung cancer it has been only rarely reported. We describe an unusual case of lung cancer (nonsmall-cell lung cancer) presenting with CVST. A 59-year-old man was admitted to our hospital with abnormal shadows on both his chest X-ray film and his chest computed tomography (CT) scans. He presented with headache, sudden onset of convulsive seizures, and higher cerebral dysfunction. A magnetic resonance (MR) scan of the brain showed high signal intensity in the left temporal cortex on T1- and T2-weighted images. Magnetic resonance venography (MRV) ultimately revealed left transverse sinus and left sigmoid sinus thrombosis. The patient was treated with anticoagulation, chemotherapy, and radiotherapy. This case represents a rare condition of CVST accompanied by lung cancer.
Lung cancer Cerebral venous thrombosis Generalized seizures Higher brain dysfunction
Received 28 Jan 2013 / Accepted 1 Apr 2013
AJRS, 2(4): 461-465, 2013