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Article in Japanese
Abstract
Case Report
Eosinophilic pleural effusion resulting from propylthiouracil
Nobuo Ishiwataa Yuko Taniguchia Naohiko Inaseb
aInternal Medicine, Kudanzaka Hospital
bDepartment of Respiratory Medicine, Tokyo Medical and Dental University
ABSTRACT
A 55-year-old man was admitted to our hospital with a complaint of slight left chest pain and dyspnea on effort of 2 months duration. He had had Basedow's disease, which had been treated with high-dose (300 mg daily) propylthiouracil (PTU) for 15 years. Chest X-ray on admission showed left moderate pleural effusion, and thoracentesis revealed eosinophilic pleural effusion (EPE). After normalization of the thyroid hormone and the anti-TSH receptor antibody had been confirmed, PTU was decreased gradually and discontinued. Since then, pleural effusion has disappeared without recurrence. We conclude that in this case, EPE was induced by a long-term use of PTU.
KEYWORDS
Eosinophilic pleural effusion Propylthiouracil
Received 22 Nov 2012 ／ Accepted 7 Mar 2013
AJRS, 2(4): 437-441, 2013
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