A case of primary lung cancer with gastric metastasis in which systemic chemotherapy was supported by tube feeding
Reiko Yoshino Yoshio Tomizawa Kousuke Takei Tomohito Kuwako Akihiro Yoshii Ryusei Saitou
Department of Respiratory Medicine, National Hospital Organization Nishigunma Hospital
A 69-year-old woman with recurrent lung adenocarcinoma after operation was treated with carboplatin, pemetrexed, and bevacizumab, followed by only bevacizumab. In the 10th course of maintenance chemotherapy with bevacizumab, she experienced passage disorder when swallowing solid food. A CT scan revealed hypertrophy of the cardiac notch region of the lesser curvature of the stomach. Upper gastrointestinal endoscopy showed stenosis of the cardiac notch region of the stomach, and a biopsy specimen from the stenotic region demonstrated metastasis of lung adenocarcinoma. We performed gastrostomy and began systemic chemotherapy with docetaxel hydrate. She regained the ability to swallow solid food around day 15 of therapy with docetaxel hydrate, and the stenosis also improved. A gastric metastasis from lung cancer is rare, and diagnosis is difficult. Because of the severity, however, detailed examination of the gastrointestinal tract is important. Furthermore, our results in this case suggest that systemic chemotherapy is useful in patients with a passage disorder concomitant to gastric metastasis if the patient's general condition is supported by tubal feeding.
Lung cancer Gastric metastasis Chemotherapy Tube feeding
Received 4 Sep 2012 / Accepted 17 Jan 2013
AJRS, 2(4): 375-379, 2013