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Article in Japanese
Abstract
Diagnostic Imaging
A fatal case of lymphoepithelioma-like carcinoma of lung
Chiyako Oshikataa Naomi Tsurikisawaa Kimihiko Miib Tomoko Ohmoric Masakazu Takigawac Yuko Tsunodad Takahiro Tsuburaia Ayako Horitae Ikuo Saitoe Kazuo Akiyamaa
aDepartment of Allergy and Respiratory Medicine, National Hospital Organization Sagamihara National Hospital
bDepartment of Neurosurgery, National Hospital Organization Sagamihara National Hospital
cDepartment of Radiology, National Hospital Organization Sagamihara National Hospital
dDepartment of Hematology, National Hospital Organization Sagamihara National Hospital
eDepartment of Laboratory Medicine, National Hospital Organization Sagamihara National Hospital
ABSTRACT
We presented a rare case of lymphoepithelioma-like carcinoma of lung in a 73-year-old Japanese woman. At first, the small nodules were near the pulmonary artery in the bilateral lobes. The size of nodules became rapidly larger within 2 weeks, and respiratory failure advanced. In Elastica van Gieson-stained histological cross-sections of the tumor, large neoplastic cells with abundant cytoplasm were seen not only around the pulmonary artery, but also in intravascular space. Tumor cells had several immunohistochemical stainings for CD3 negative, CD20 negative, AE1/AE3 positive, and EBER-1 positive. About 90% of tumor cells were positive by immunohistochemical staining for MIB-1. These pathological features indicate that this case presented a poor prognosis.
KEYWORDS
Lymphoepithelioma-like carcinoma of lung Lymphomatoid granulomatosis
Received 13 Jan 2012 ／ Accepted 11 Sep 2012
AJRS, 2(3): 316-320, 2013
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