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Article in Japanese
Abstract
Case Report
Obstinate hyponatremia and hypoglycemia caused by pituitary metastasis of lung cancer
Kakuhiro Yamaguchi Soichi Kitaguchi Mayuko Kagawa Takashi Ogawa Fumihiro Sugahara Hiromi Egawa
Department of Respiratory Medicine, Hiroshima City Asa Hospital
ABSTRACT
A 66-year-old male was admitted with fatigue and weight loss. A CT examination revealed a 10-mm lung nodule in the left S8 region, right supraclavicular adenopathy, multiple brain metastases, and multiple pancreatic metastases. We diagnosed the patient with small cell lung cancer based on the results of a right supraclavicular adenopathy biopsy. The laboratory data showed low values of cortisol, hyponatremia, and hypoglycemia. The patient underwent hormonal replacement therapy to improve hypopituitarism caused by pituitary metastasis. His performance status quickly improved, and he became able to receive chemotherapy. Hypopituitarism occurring in a patient with pituitary metastasis of lung cancer is rare. However, it is very important to improve the hormonal condition of patients using early medical intervention to prolong their survival.
KEYWORDS
Lung cancer Pituitary metastasis Hypopituitarism Hyponatremia Hypoglycemia
Received 15 Aug 2012 ／ Accepted 8 Nov 2012
AJRS, 2(3): 279-283, 2013
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