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Abstract

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Article in Japanese

Case Report

Invasive pulmonary aspergillosis following therapy for bronchial asthma attack: A case report

Yusuke Inouea,b  Katsuhiro Yoshimuraa  Minako Omaea  Yoshiko Satoa  Koshi Yokomuraa  Takafumi Sudab  Kingo Chidab 

aDepartment of Respiratory Medicine, Respiratory Disease Center, Seirei Mikatahara Hospital
bSecond Department of Internal Medicine, Hamamatsu University School of Medicine

ABSTRACT

A 76-year-old female with a bronchial asthma attack complicated by a Pseudomonas aeruginosa lower respiratory tract infection was treated with systemic corticosteroids and antibiotics. She subsequently developed invasive pulmonary aspergillosis that was treated successfully with micafungin and voriconazole. Systemic corticosteroids and injury of bronchial mucosa resulting from bronchitis were considered major contributing factors. Invasive pulmonary aspergillosis has been a rare occurrence in patients with bronchial asthma, and it has been reported in only a few cases. Physicians, however, are cautioned to be alert for evidence of invasive aspergillosis in asthmatic patients receiving corticosteroid therapy.

KEYWORDS

Invasive pulmonary aspergillosis  Bronchial asthma  Steroid  Antifungal treatment 

Received 26 Mar 2012 / Accepted 9 Jul 2012

AJRS, 2(1): 53-58, 2013

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