Invasive pulmonary aspergillosis following therapy for bronchial asthma attack: A case report
Yusuke Inouea,b Katsuhiro Yoshimuraa Minako Omaea Yoshiko Satoa Koshi Yokomuraa Takafumi Sudab Kingo Chidab
aDepartment of Respiratory Medicine, Respiratory Disease Center, Seirei Mikatahara Hospital
bSecond Department of Internal Medicine, Hamamatsu University School of Medicine
A 76-year-old female with a bronchial asthma attack complicated by a Pseudomonas aeruginosa lower respiratory tract infection was treated with systemic corticosteroids and antibiotics. She subsequently developed invasive pulmonary aspergillosis that was treated successfully with micafungin and voriconazole. Systemic corticosteroids and injury of bronchial mucosa resulting from bronchitis were considered major contributing factors. Invasive pulmonary aspergillosis has been a rare occurrence in patients with bronchial asthma, and it has been reported in only a few cases. Physicians, however, are cautioned to be alert for evidence of invasive aspergillosis in asthmatic patients receiving corticosteroid therapy.
Invasive pulmonary aspergillosis Bronchial asthma Steroid Antifungal treatment
Received 26 Mar 2012 / Accepted 9 Jul 2012
AJRS, 2(1): 53-58, 2013