A 19-year-old man was admitted to our hospital with a cough, chest pain, and hemosputum. A chest X-ray and computed tomography scan showed multiple lesions in both lung fields. From a cervical lymph node biopsy, Hodgkin’s lymphoma was diagnosed, but because it was necessary to rule out acid-fast bacterium disease or mycosis of lung lesions, we performed a thoracoscopic lung biopsy for diagnostic purposes. The resected lung tissue specimen showed CD30 positive, large atypical cells; no acid-fast bacterium or fungi were found. Therefore we diagnosed pulmonary infiltration by a Hodgkin’s lymphoma. There was a blood vessel in the center of the lung tumor, which was obstructed by an invasion of neoplastic cells. This suggests that the hollow pulmonary lesions were formed by extensive necrosis. The pulmonary shadow disappeared with an administration of chemotherapy. We wish to report this rare case of Hodgkin’s lymphoma with multiple cavitary pulmonary lesions at the time of the initial presentation.